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View Full Version : Transient Anaemia & Hyperlipidaemia in Kittens - My Recent Experience


merlin's mum
09-03-2007, 12:50 AM
I want to share with you my recent experience with my current litter - who I hasten to add are now tearing around my living room! It's, apparently, a rare condition and there is not a lot of research about it but a paper exists which was published in 1997. Glasgow Vet School are doing some further research into it and into why my kittens were affected. I believe in being open and honest about problems which occur since this is the only way we, as breeders, can really work out how frequently a problem occurs and thereby go some way towards finding out how to prevent it/eradicate it from the breed. Anyway, enough of that, here's what happened.

After a normal pregnancy and an easy birth, Sophie's kittens grew well with no signs of problems until they were five weeks old. Suddenly, on the Monday evening, one of the boys developed a paralysis of the back legs. Since one of the boys had flung himself from my arms to the hard floor, we thought he must have sustained an injury and rushed him to the vets. Obviously our vet was very concerned but the kitten was happy and otherwise quite settled. The following morning, he wasn't any different and she felt we ought to try to see what had caused the paralysis. As he was so young, and therefore small, she felt he would be best off seen by the Neurologists at Glasgow Vet School and I rushed him off down to Glasgow. There wasn't any injury but he was diagnosed with a clot in his aorta where it branched for his back legs. My little boy was transferred to the Medicine team and his blood was tested to see why he might have developed a clot. He was much more anaemic than kittens of that age might reasonably be expected to be (given that they're likely to be anaemic when they have mainly been receiving mother's milk until that time and it's low in iron). He also had high levels of lipids in his blood - high levels of fat. This fitted with a condition referred to as Transient Anaemia and Hyperlipidaemia. This affects kittens typically around weaning time - between four and seven weeks of age. Usually the whole litter is affected and it's associated with high levels of mortality if not treated. However, it can easily be diagnosed and treated by switching the kittens and their mother to a low-fat diet. The level of anaemia drops quickly and the levels of fat in the blood usually return to normal quickly. Paralysis of the hindlimbs is one of the possible clinical signs along with lack of appetite and difficulty breathing, although none of my kittens had those symptoms. My kitten was at Glasgow Vet School for four days and returned home to be welcomed back by his siblings and mother without any problem. When he returned, he was walking reasonably normally and running around like a race horse - no doubt delighted to have lots of room to run around in again. By the following day, he was walking pretty well normally and running everywhere. Now he jumps and walks well and runs so that we can't tell him apart from the others. One of the other kittens had abnormal levels of fat and was quite severely anaemic but never developed any clinical signs either we or the vets could detect. They had their blood tested again about 8 days after they were switched to a low-fat diet and none of them are now anaemic and none of them have high fat levels in their blood. They continue to grow normally and behave exactly like we all expect seven week old, healthy kittens to grow.

The condition may well be caused by feeding the queen too high a fat diet during pregnancy and nursing and by feeding the kittens too high a fat diet when they start to be weaned.

I want everyone to know about the existence of this condition so that, no matter how rarely it occurs, no kittens are put to sleep because they have, apparently, sustained an injury which causes paralysis of the hind legs from which their vet thinks they might not recover. Very few vets will know of this condition. Equally, I'd rather feel that breeders will not lose kittens - perhaps even a whole litter - to a condition which can very easily be diagnosed and treated. Sophie's breeder was told, back in 1987, not to feed Siamese cats on a diet higher than 14% fat and has had no problems since then. Having had a litter go through this experience, she has never fed a wholly commercial dry diet to her cats since.

Sophie was fed on Royal Canin's Babycat 34 and Kitten 34 during her pregnancy and whilst nursing her kittens - right up to when the problem was first experienced. Our kittens were weaned on mainly Babycat 34 with some Applaws tins (which is fine as it's not high in fat). Whilst Royal Canin make a Siamese diet, which is probably a good diet for Siamese to be on generally, it's likely to be too low in fat for a sole diet whilst pregnant and it's probably not suitable for kittens to be weaned on to (bearing in mind that they say it's definitely not!). I'm not suggesting a solution to the issue of diet but my experience this time has certainly made me feel strongly that the 'no more than 14% fat' suggestion has definite merit and I intend to stick to this for the future.

Glasgow Vet School, together with Bristol, are researching my litter's experience further and I will provide more information as it becomes available, but for now that's all there is. If you, or anyone you know, has had an experience similar to this - even if this condition was not diagnosed, I would be interested to hear about it.

Lucia
09-03-2007, 08:37 AM
I'm not a breeder, but I have a keen interest in all things medical and thoroughly enjoyed reading your excellent, informative and impressive account of the management of a syndrome I'd not heard of before.
I'm so glad that everything turned out positively for your kittens! :)

siany
09-03-2007, 08:57 AM
I'm not a breeder, but I have a keen interest in all things medical and thoroughly enjoyed reading your excellent, informative and impressive account of the management of a syndrome I'd not heard of before.
I'm so glad that everything turned out positively for your kittens! :)

I too am not a breeder but i found your posting very interesting and informative. It's great that that all is positive for your kittens
xx

audrey
09-03-2007, 10:28 AM
I've been breeding for nearly 30 years, I've never come across it, but when I first started breeding I was advised not to give them much dried food, I feed a mixture of sachets, applaws, fresh cooked meat ( chicken, rabbit, turkey ), tuna and fresh cooked coley, and they have a dish of mixed biscuits, RC, JWB, and Pets at home own brand, I also give kittens a little raw minced beef, human quality, my kitten recipes are on my website.
It sounds as though the Manufacturers need to be made aware of this and then maybe they can reduce the fat content.

Judi
09-03-2007, 11:07 AM
My cats have pouches but with dried food available at will. That article was really interesting. I'm glad everyone is now well and tearing up the house - I don't know how you cope - I only have 1 kitten and he sounds like a herd of elephants just on his own.

Judi

Helens Girls
09-03-2007, 11:31 AM
Thats very interesting to read, glad all is well now.
My cats have pouches, canned tuna in brine with a little grated cheese, fresh chicken, kitten has one serving of her kitten Royal Canin 34, other cats prefer Iams. Vet advised they have some dried food to help keep teeth clean. They only drink water too.

Carole
09-03-2007, 12:16 PM
That's fascinating. Veterinary medicine seems to be discovering all kinds of answers to mysterious illnesses in cats these days.
I'm just wondering if this might have any connection with the fading kitten problems?

Carole

Mochali
09-03-2007, 05:08 PM
Ruby being on a mix of RC Siamese38 and queen34 will be ok then! Phew!
She also has adult wet food, either felix/whiskas!

audrey
09-03-2007, 05:30 PM
The manufacturers recommend that RC Siamese is not given to kittens, pregnant or nursing queens.

Mochali
09-03-2007, 08:06 PM
The manufacturers recommend that RC Siamese is not given to kittens, pregnant or nursing queens.

How come?
Its the only thing she is eating, apart from the queen34!

audrey
09-03-2007, 09:32 PM
When we tested it for RC we were told then that it wasn't suitable for them, and it probably says it on the bag.

Mochali
09-03-2007, 11:26 PM
I will email Christian!

audrey
09-03-2007, 11:28 PM
Have you looked on the bag ?

merlin's mum
10-03-2007, 01:46 AM
When I originally fed RC Siamese, I had a conversation with RC about why it wasn't suitable for pregnant and nursing queens and kittens - it's too low in fat! Before I tried the Siamese diet, I read through all the analyses of the different foods RC offer (which used to be available online but now isn't!), and I remember the fat level being very low indeed - lower even than their weight loss diet of the time. It will be different in other ways, too.

I haven't contacted RC about this issue at the moment. I don't honestly think they're alone in this as all dry diets - whatever brand - for kittens and nursing queens are likely to be high in fat - this is what is generally recommended - it just might not be appropriate for our breed. When the research is complete, if it is able to conclude fairly certainly that diet is what caused the problem I had, I will contact RC myself and let them know all about it. Perhaps they would, then, be willing to develop a diet for Siamese kittens and this could be fed to the queens as well.

Please note, everyone, that I'm certainly not blaming RC for causing the problem with my kittens as their advice and products fit very much with usual advice for feeding pregnant and nursing queens and weaning kittens.

Thanks very much for all the supportive posts. It's good to be able to discuss the issue with other breeders and to know that more people know about the possibility of this happening than did before.

As far as whether it could be linked with 'fading kitten syndrome', is that not associated with a mismatching of blood groups? From the little I gather, Siamese are almost exclusively, if not actually exclusively, Group A. However, if you mean could it be linked with kittens who just die unexpectedly with nothing else apparently wrong with them, it appears to affect kittens around the weaning age, so it depends when they die. If it's shortly after birth or within the first three weeks, possibly not, but I don't know if enough is known about that aspect. It's fair to say that, often, a post-mortem is not done on kittens who die at a young age and, therefore, much may be missed. However, it's distressing enough to lose a kitten and perhaps many can't face having a post-mortem carried out. It's also possible your vet may not give you the opportunity unless you specifically ask in advance.

Thanks, Audrey, for your feeding advice - I am going to be moving my cats and kittens over to a similar feeding regime early next week after they have completed their final week on the Obesity diet. Many breeders recommend such a feeding regime and I've always followed the commercial dry diet manufacturers advice that sticking with one brand and one diet is the best way to ensure a balanced diet. As I said before, I now feel it's time to try a more natural diet.

Thanks, everyone, for joining in the discussion, and I look forward to reading more replies over time.

audrey
10-03-2007, 11:37 AM
Trouble is manufacturers are in it for money, so their advice is biased, as of course they don't want you to use their rival's biscuits.

merlin's mum
11-03-2007, 01:46 AM
You're right, of course, Audrey - and it's expensive to redesign a food. Unless sufficient evidence of this and other problems connected with too high a fat content turn up, it's likely they won't do anything at all. However, at least I will be able to tell myself that I tried. Equally, I can look out for my own kittens and cats and make sure mine don't suffer problems related to fat levels of diet.